Spatial epitranscriptomics reveals A-to-I editome specific to cancer stem cell microniches
oleh: Amos C. Lee, Yongju Lee, Ahyoun Choi, Han-Byoel Lee, Kyoungseob Shin, Hyunho Lee, Ji Young Kim, Han Suk Ryu, Hoe Suk Kim, Seung Yeon Ryu, Sangeun Lee, Jong-Ho Cheun, Duck Kyun Yoo, Sumin Lee, Hansol Choi, Taehoon Ryu, Huiran Yeom, Namphil Kim, Jinsung Noh, Yonghee Lee, Inyoung Kim, Sangwook Bae, Jinhyun Kim, Wooseok Lee, Okju Kim, Yushin Jung, Changhoe Kim, Seo Woo Song, Yeongjae Choi, Junho Chung, Byung Gee Kim, Wonshik Han, Sunghoon Kwon
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
The spatial context of epitranscriptomic features in the tumour microenvironment remains poorly understood. Here, a method for transcriptomic and epitranscriptomic analysis of immunofluorescence-stained tissue, Select-seq, is applied to stem cell-like microniches in triple negative breast cancer.