MME+ fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle
oleh: Gillian Fitzgerald, Guillermo Turiel, Tatiane Gorski, Inés Soro-Arnaiz, Jing Zhang, Nicola C. Casartelli, Evi Masschelein, Nicola A. Maffiuletti, Reto Sutter, Michael Leunig, Jean Farup, Katrien De Bock
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Using single nuclei and single cell RNA-seq, 3 FAP cell subpopulations are identified in human skeletal muscle, with an MME+ subset showing increased adipogenic potential under fatty infiltration conditions.