ABHD4-dependent developmental anoikis safeguards the embryonic brain
oleh: Zsófia I. László, Zsolt Lele, Miklós Zöldi, Vivien Miczán, Fruzsina Mógor, Gabriel M. Simon, Ken Mackie, Imre Kacskovics, Benjamin F. Cravatt, István Katona
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-08-01 |
Deskripsi
During embryonic development, neural progenitor cells undergo numerous cell divisions. Here, the authors show that ABHD4-mediated developmental anoikis distinguishes the physiological delamination and the pathological detachment of progenitor cells with relevance to fetal alcohol-induced apoptosis.