Quantifying cell-generated forces: Poisson’s ratio matters

oleh: Yousef Javanmardi, Huw Colin-York, Nicolas Szita, Marco Fritzsche, Emad Moeendarbary

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Mechanical forces play important roles in cell biology and traction force microscopy (TFM) experiments have enabled quantification of the cell-generated forces when placed on substrates of distinct stiffnesses. Here the authors evaluate the effect of the Poisson’s ratio- one of the main descriptors of the material’s mechanical behaviour together with the Elastic Modulus, in the context of TFM experiments.