Unraveling FOXO3a and USP18 Functions in Idiopathic Pulmonary Fibrosis through Single-Cell RNA Sequencing of Mouse and Human Lungs
oleh: Ban Wang, Jichun Pan, Zhonghui Liu
| Format: | Article |
|---|---|
| Diterbitkan: | Georg Thieme Verlag KG 2023-12-01 |
Deskripsi
Background Idiopathic pulmonary fibrosis (IPF) is identified as a chronic, progressive lung disease, predominantly marked by enhanced fibroblast proliferation and excessive deposition of extracellular matrix. The intricate interactions between diverse molecular pathways in fibroblasts play a crucial role in driving the pathogenesis of IPF.