Toxin import through the antibiotic efflux channel TolC
oleh: Nicholas G. Housden, Melissa N. Webby, Edward D. Lowe, Tarick J. El-Baba, Renata Kaminska, Christina Redfield, Carol V. Robinson, Colin Kleanthous
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-07-01 |
Deskripsi
Bacteria can secrete diffusible protein toxins that kill competing bacteria. Here, the authors use biochemical, biophysical and structural analyses to show how one of these toxins exploits TolC (a major antibiotic efflux channel) to transport itself across the outer membrane of target cells.