Synthesis of New Homodrimane Sesquiterpenoids Containing Diazine, 1,2,4-triazole and Carbazole Rings
oleh: Gheorghe Duca, Aculina Aricu, Lidia Lungu, Nadejda Tenu, Alexandru Ciocarlan, Yacob Gutu, Ion Dragalin, Alic Barba
| Format: | Article |
|---|---|
| Diterbitkan: | Academy of Sciences of Moldova, Institute of Chemistry 2018-06-01 |
Deskripsi
The study describes the synthesis of 11-homodrim-6,8-dien-12-oic acid N-substituted amides containing diazine, 1,2,4-triazole and carbazole rings based on commercially available sclareolide. The mentioned compounds were prepared for the first time by interaction of the generated in situ acyl chloride with some heterocyclic amines: 2- and 4-aminopyrimidine, 2-aminopyrazine, 3-amino-1,2,4-triazole and N-aminocarbazole. Their structures were fully elucidated by elemental and spectral analyses (IR, 1H and 13C NMR).