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Abstract In this paper, we consider two-flavor QCD at zero temperature and finite isospin chemical potential $$\mu _I$$ μ I using a model-independent analysis within chiral perturbation theory at next-to-leading order. We calculate the effective potential, the chiral condensate and the pion condensate in the pion-condensed phase at both zero and nonzero pionic source. We compare our finite pionic source results for the chiral condensate and the pion condensate with recent (2+1)-flavor lattice QCD results. Agreement with lattice results generally improves as one goes from leading order to next-to-leading order.