Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation

oleh: Abdulrahim A. Sajini, Nila Roy Choudhury, Rebecca E. Wagner, Susanne Bornelöv, Tommaso Selmi, Christos Spanos, Sabine Dietmann, Juri Rappsilber, Gracjan Michlewski, Michaela Frye

Format: Article
Diterbitkan: Nature Portfolio 2019-06-01

Deskripsi

RNA modifications, including 5-methylcytosines, are known regulators of RNA metabolism affecting protein-RNA binding. Here, the authors reveal the role of m5C in the biogenesis of the non-coding vault-derived small RNAs.