Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
oleh: Jonathan D. Rubin, Jacob T. Stanley, Rutendo F. Sigauke, Cecilia B. Levandowski, Zachary L. Maas, Jessica Westfall, Dylan J. Taatjes, Robin D. Dowell
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-06-01 |
Deskripsi
Rubin et al. introduce transcription factor enrichment analysis (TFEA), a new motif enrichment method specifically aimed at maximizing the informative nature of differential RNA polymerase initiation data. It provides an easy, rigorous, and cost-effective analysis aimed at deciphering the temporal and mechanistic details of complex regulatory networks.