Diverse Humoral Immune Responses in Younger and Older Adult COVID-19 Patients
oleh: Jennifer M. Sasson, Joseph J. Campo, Rebecca M. Carpenter, Mary K. Young, Arlo Z. Randall, Krista Trappl-Kimmons, Amit Oberai, Christopher Hung, Joshua Edgar, Andy A. Teng, Jozelyn V. Pablo, Xiaowu Liang, Angela Yee, William A. Petri, David Camerini
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-06-01 |
Deskripsi
As numerous viral variants continue to emerge in the coronavirus disease 2019 (COVID-19) pandemic, determining antibody reactivity to SARS-CoV-2 epitopes becomes essential in discerning changes in the immune response to infection over time. This study enabled us to identify specific areas of antigenicity within the SARS-CoV-2 proteome, allowing us to detect correlations of epitopes with clinical metadata and immunological signals to gain holistic insight into SARS-CoV-2 infection.