Progressive Multifocal Leukoencephalopathy after Treatment with Nivolumab
oleh: Martin Martinot, Guido Ahle, Inesa Petrosyan, Camille Martinez, Dragos M. Gorun, Mahsa Mohseni-Zadeh, Samira Fafi-Kremer, Martine Tebacher-Alt
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2018-08-01 |
Deskripsi
Progressive multifocal leukoencephalopathy (PML) is increasingly being reported in patients undergoing immunotherapy. We report a case of progressive multifocal leukoencephalopathy after treatment with nivolumab, a PD-1 blocker that is used to restore impaired T-cell responses in patients with cancer and infections. Data for 4 other cases were obtained from pharmacovigilance databases.