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Objective: Our aim is reappraisal of Mitrofanoff prin-ciple in a wide array of diverse clinical situations like pelvic tumors, myelodysplasia, irreparably damaged ure-thra and sphincters and with total bladder substitution. Materials and Methods: 24 patients underwent the con-struction of a continent catheterisable stoma based on the Mitrofanoff principle between February 1990 to Decem-ber 2000 for various etiologies. Youngest patient was 4 years old and the oldest patient was 54 years of age. The conduit was constructed using appendix in all patients. Results: Stomal continence was achieved in all 24 pa-tients (100%). Difficulty in catheterisation was most fre-quent late complication encountered in 4 patients (16.6%). 3 patients (12.45%) developed stones in reservoir Conclusions: Mitrofanoff procedure is a versatile tech-nique. The extension of this principle can provide conti-nence mechanism to variety of patients, with or without total or partial substitution of bladder, in whom there is no usable urethra or sphincter or both.