Regulation of nuclear mTORC1

oleh: Xin Zhou, Yanghao Zhong, Jin Zhang

Format: Article
Diterbitkan: Taylor & Francis Group 2021-05-01

Deskripsi

mTORC1 integrates diverse upstream signals to control cell growth and metabolism. We previously showed that mTORC1 activity is spatially compartmentalized to ensure its signaling specificity. In a recently published study, we demonstrated the existence of mTORC1 activity in the nucleus and identified a unique mode of its regulation in the nuclear compartment.