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Regulation of nuclear mTORC1
oleh: Xin Zhou, Yanghao Zhong, Jin Zhang
Format: | Article |
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Diterbitkan: | Taylor & Francis Group 2021-05-01 |
Deskripsi
mTORC1 integrates diverse upstream signals to control cell growth and metabolism. We previously showed that mTORC1 activity is spatially compartmentalized to ensure its signaling specificity. In a recently published study, we demonstrated the existence of mTORC1 activity in the nucleus and identified a unique mode of its regulation in the nuclear compartment.