Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
oleh: Ake T. Lu, Eilis Hannon, Morgan E. Levine, Eileen M. Crimmins, Katie Lunnon, Jonathan Mill, Daniel H. Geschwind, Steve Horvath
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-05-01 |
Deskripsi
Studies on the ‘epigenetic clock’, a recently identified ageing biomarker, suggest that pathology might be linked to tissue-specific accelerated ageing. Here, the authors investigate ageing in the human brain and identify genetic loci associated with accelerated ageing in different brain regions.