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Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation
oleh: Valentin Mitterer, Guillaume Murat, Stéphane Réty, Magali Blaud, Lila Delbos, Tamsyn Stanborough, Helmut Bergler, Nicolas Leulliot, Dieter Kressler, Brigitte Pertschy
Format: | Article |
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Diterbitkan: | Nature Portfolio 2016-02-01 |
Deskripsi
Ribosome biogenesis involves the hierarchical assembly of several proteins and RNA components. Here the authors describe a mechanism for ribosomal protein S3 incorporation into 40S ribosomal subunits that involves S3 dimerization and stepwise incorporation of two distinct S3 interaction domains coupled to release of ribosomal maturation factors.