Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review

oleh: Prakriti Singh Shrestha, Angela Ishak, Arun R. Napit, Sarosh Sarwar, Niraj Rai, Zoha Nizami, Niharika Bheemisetty, Prashanth Jayaraj, Amardeep Shrestha, Ivan D. Rodriguez

Format: Article
Diterbitkan: Elsevier 2022-01-01

Deskripsi

Thrombosis following COVID-19 vaccination commonly occurs with vector-based vaccines. The proposed mechanism is vaccine-induced thrombotic thrombocytopenia (VITT), with thrombocytopenia as principal manifestation. We present a 51-year-old male who came with isolated portal vein thrombosis (PVT) one day after Moderna vaccination, without associated thrombocytopenia, challenging VITT as being the only patho-mechanism. Further exploration of these possible alternative mechanisms is needed for COVID-19 vaccine-related thrombotic complications.