Perfil de flavonoides e avaliação do potencial antioxidante e citotóxico de Bauhinia purpurea (Fabaceae) da região amazônica
oleh: Priscila Moraes dos Santos, Patrícia Danielle Oliveira de Almeida, Emerson Silva Lima, Manoel Odorico de Moraes, Patrícia Marçal da Costa, Assuero Silva Meira, Cláudia do Ó Pessoa, Ligia Maria Marino Valente, Valdir Florêncio da Veiga Junior
| Format: | Article |
|---|---|
| Diterbitkan: | Sociedade Brasileira de Química 2014-01-01 |
Deskripsi
Bauhinia purpurea (Fabaceae). Plants of the Bauhinia species (Fabaceae) are used in the treatment of several infections and diseases, especially diabetes. In this paper, with an aim to contribute to the knowledge of the chemistry and therapeutic potential of the Amazonian species of the genus Bauhinia, flavonoid profiles in the leaves and branches of Bauhinia purpurea collected in Manaus and São Gabriel da Cachoeira/AM were analyzed by HPLC-DAD and ESIMS. Differences in the flavonoid profiles were detected along with the presence of rutin and isoquercitrin in the leaves collected in Manaus. All samples showed antioxidant activity, however, no cytotoxic activity against cell lines MDA-MB435 (breast), HCT-8 (colon), and SF-295 (glioblastoma) could be detected.