Identification of mouse cochlear progenitors that develop hair and supporting cells in the organ of Corti

oleh: Jinshu Xu, Hiroo Ueno, Chelsea Y. Xu, Binglai Chen, Irving L. Weissman, Pin-Xian Xu

Format: Article
Diterbitkan: Nature Portfolio 2017-05-01

Deskripsi

The adult mammalian cochlear sensory epithelium consists of mechanosensory hair cells and supporting cells but hair cells cannot regenerate. Here, the authors identify multipotent progenitors that arise fromEya1-expressing otic cells that can regenerate hair cells in mice after 1 week of age.