Advancing our understanding of genetic risk factors and potential personalized strategies for pelvic organ prolapse

oleh: Natàlia Pujol-Gualdo, Kristi Läll, Maarja Lepamets, Estonian Biobank Research Team, Henna-Riikka Rossi, Riikka K. Arffman, Terhi T. Piltonen, Reedik Mägi, Triin Laisk

Format: Article
Diterbitkan: Nature Portfolio 2022-06-01

Deskripsi

Although pelvic organ prolapse is a common gynecological condition, the genetic component of disease risk is not well known. Here the authors find common genetic variants associated with the disease and present a polygenic risk score to enhance individual risk prediction.