MicroRNAs from Snellenius manilae bracovirus regulate innate and cellular immune responses of its host Spodoptera litura
oleh: Cheng-Kang Tang, Chih-Hsuan Tsai, Carol-P. Wu, Yu-Hsien Lin, Sung-Chan Wei, Yun-Heng Lu, Cheng-Hsun Li, Yueh-Lung Wu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
Tang et al. show that microRNAs derived from an endoparasitic wasp Snellenius manilae bracovirus (SmBV), SmBV-miR-199b-5p and SmBV-miR-2989, target domeless and toll-7 in its host Spodoptera litura, suppressing the innate immune responses of parasitized hosts. This study provides insights into how parasites maximize their fitness by regulating host immunity.