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The complete chloroplast genome sequence of Homalium cochinchinense was characterized from Illumina pair-end sequencing. The chloroplast genome of H .cochinchinense was 157,116 bp in length, containing a large single-copy region (LSC) of 85,194 bp, a small single-copy region (SSC) of 16,650 bp, and two inverted repeat (IR) regions of 27,636 bp. The overall GC content is 36.6%, while the corresponding values of the LSC, SSC, and IR regions are 64.9%, 69.2%, and 60.3%, respectively. The genome contains 122 complete genes, including 86 protein-coding genes (77 protein-coding gene species), 36 tRNA genes (29 tRNA species) and 8 rRNA genes(4 rRNA species). The Neighbour-joining phylogenetic analysis showed that H. cochinchinense and Flacourtia indica clustered together as sisters to other Salicaceae species, and suggested that this clade may be an ancestral lineage as observed in the phylogenetic tree.