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Altered regulation of mesenchymal cell senescence in adipose tissue promotes pathological changes associated with diabetic wound healing
oleh: Arisa Kita, Yuki Saito, Norihiro Miura, Maki Miyajima, Sena Yamamoto, Tsukasa Sato, Takatoshi Yotsuyanagi, Mineko Fujimiya, Takako S. Chikenji
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-04-01 |
Deskripsi
Type-2 diabetic adipose tissue impairs transient senescence during wound healing with expression of different components of the senescence-associated secretory phenotype (SASP), and this is associated with deteriorated wound healing.