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<p>Current plight of COVID-19 in developing countries entails uncertain prognosis, impending severe shortages of resources for testing and treatment and inadequate safety measure for health care providers. The imposition of unfamiliar public health measures that may infringe on personal freedoms, large and growing financial losses, and conflicting messages from authorities are among the other major stressors that undoubtedly will contribute to widespread emotional distress and increased risk for mental fatigue associated with COVID-19.</p>