The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors

oleh: Xuhui Zheng, Gerben Marsman, Keenan A. Lacey, Jessica R. Chapman, Christian Goosmann, Beatrix M. Ueberheide, Victor J. Torres

Format: Article
Diterbitkan: Nature Portfolio 2021-10-01

Deskripsi

The pathogen Staphylococcus aureus releases several pore-forming toxins, termed leukocidins, that kill immune cells. Here, Zheng et al. show that the retention of a leukocidin on bacterial cells and its release are modulated by lipoteichoic acid and a membrane lipid, which also control the sorting of other surface-associated proteins.