Tunable, biodegradable grafting-from glycopolypeptide bottlebrush polymers
oleh: Zachary S. Clauss, Casia L. Wardzala, Austin E. Schlirf, Nathaniel S. Wright, Simranpreet S. Saini, Bibiana Onoa, Carlos Bustamante, Jessica R. Kramer
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Synthetic mimics of glycoproteins and proteoglycans have wide applications in biomedicine, yet preparation has been challenged by their high grafting and glycosylation densities. Here the authors show one-pot dual-catalysis polymerization of glycan-bearing α-amino acid N-carboxyanhydrides to form glycopolypeptide brushes.