Synthesis of Indenones via Persulfate Promoted Radical Alkylation/Cyclization of Biaryl Ynones with 1,4-Dihydropyridines

oleh: Wanwan Wang, Lei Yu

Format: Article
Diterbitkan: MDPI AG 2024-01-01

Deskripsi

The oxidative radical cascade cyclization of alkynes has emerged as a versatile strategy for the efficient construction of diverse structural units and complex molecules in organic chemistry. This work reports an alkyl radical initiated 5-<i>exo</i>-trig cyclization of biaryl ynones with 1,4-dihydropyridines to selectively synthesize indenones.