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Synthesis of Indenones via Persulfate Promoted Radical Alkylation/Cyclization of Biaryl Ynones with 1,4-Dihydropyridines
oleh: Wanwan Wang, Lei Yu
Format: | Article |
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Diterbitkan: | MDPI AG 2024-01-01 |
Deskripsi
The oxidative radical cascade cyclization of alkynes has emerged as a versatile strategy for the efficient construction of diverse structural units and complex molecules in organic chemistry. This work reports an alkyl radical initiated 5-<i>exo</i>-trig cyclization of biaryl ynones with 1,4-dihydropyridines to selectively synthesize indenones.