Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge

oleh: Jinsheng Wen, Annie Elong Ngono, Jose Angel Regla-Nava, Kenneth Kim, Matthew J. Gorman, Michael S. Diamond, Sujan Shresta

Format: Article
Diterbitkan: Nature Portfolio 2017-11-01

Deskripsi

Dengue virus-specific antibody and CD8+ T cells that cross-react with Zika virus have been described. Here, the authors establish a functionally protective role for cross-reactive dengue virus-specific CD8+ T cells during challenge with Zika virus.