Find in Library

Oxidative coupling reactions are a very powerful tool for the construction of e.g. biaryl compounds, especially because typically no functionalization of the coupling partners is necessary. The use of Au for this transformation is particularly attractive since usually no special precautions to exclude moisture or air are necessary. Furthermore, the combination of oxidative coupling reactions with other Au-catalyzed reactions enables the rapid and efficient construction of molecular complexity, e.g. the constructions of dicoumarins via a domino cyclization oxidative coupling reaction.