Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses
oleh: Mario Reiser, Anita Girelli, Anastasia Ragulskaya, Sudipta Das, Sharon Berkowicz, Maddalena Bin, Marjorie Ladd-Parada, Mariia Filianina, Hanna-Friederike Poggemann, Nafisa Begam, Mohammad Sayed Akhundzadeh, Sonja Timmermann, Lisa Randolph, Yuriy Chushkin, Tilo Seydel, Ulrike Boesenberg, Jörg Hallmann, Johannes Möller, Angel Rodriguez-Fernandez, Robert Rosca, Robert Schaffer, Markus Scholz, Roman Shayduk, Alexey Zozulya, Anders Madsen, Frank Schreiber, Fajun Zhang, Fivos Perakis, Christian Gutt
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-09-01 |
Deskripsi
The European X-ray FreeElectron Laser Facility generates ultrashort hard X-ray pulses with megahertz repetition rate. Here, the authors probe the dynamics of dense antibody protein (Ig-PEG) solutions using megahertz X-ray photon correlation spectroscopy at the European XFEL.