TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

oleh: Limin Zhao, Hao Ke, Haibo Xu, Guo-Dong Wang, Honglei Zhang, Li Zou, Shu Xiang, Mengyuan Li, Li Peng, Mingfang Zhou, Lingling Li, Lei Ao, Qin Yang, Che-Kun James Shen, Ping Yi, Lu Wang, Baowei Jiao

Format: Article
Diterbitkan: Nature Portfolio 2020-01-01

Deskripsi

Milk lipid secretion is a critical process for the delivery of nutrition and energy from parent to offspring. Here the authors found that TDP-43, a RNA-binding protein, is required for milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh mRNA stability.