Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

oleh: Yi Liu, Hyon-Xhi Tan, Marios Koutsakos, Sinthujan Jegaskanda, Robyn Esterbauer, Danielle Tilmanis, Malet Aban, Katherine Kedzierska, Aeron C. Hurt, Stephen J. Kent, Adam K. Wheatley

Format: Article
Diterbitkan: Nature Portfolio 2019-01-01

Deskripsi

Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine design.