Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation
oleh: Neophytos Christodoulou, Antonia Weberling, Douglas Strathdee, Kurt I. Anderson, Paul Timpson, Magdalena Zernicka-Goetz
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-08-01 |
Deskripsi
How the shape of the pre-implantation murine embryo changes dramatically upon implantation is unclear. Here, the authors use live imaging with a cdx2-GFP reporter line in combination with loss of function experiments to demonstrate that FGF signalling mediated trophectoderm morphogenesis orchestrates this process.