ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection
oleh: Shousheng Ni, Yang Zhou, Lili Song, Yan Chen, Xia Wang, Xiaoyuan Du, Shicui Zhang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-02-01 |
Deskripsi
Ni et al. show that RNA-binding protein ELAVL1a is abundantly stored in the eggs and embryos of zebrafish, serving as a first-line innate immune player. They find that ELAVL1a recognizes molecular patterns of bacteria to inhibit bacterial growth. This study suggests that ELAVL1a is a maternal immune factor protecting zebrafish embryos from bacterial infection.