Afadin couples RAS GTPases to the polarity rheostat Scribble
oleh: Marilyn Goudreault, Valérie Gagné, Chang Hwa Jo, Swati Singh, Ryan C. Killoran, Anne-Claude Gingras, Matthew J. Smith
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-08-01 |
Deskripsi
Goudreault et al. investigate the role of Afadin downstream of RAS GTPases, substantiating this cell adhesion protein as a true RAS effector that couples its activation to cell polarity through the Scribble protein.