Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography

oleh: Xin-Ying Li, Mei Yang, Jie-Yun Huang, Xiao-Xue Yu, Min-Qian Zhao, Zhi-Kun Liang, Zhi-Sheng Xie, Xin-Jun Xu

Format: Article
Diterbitkan: Elsevier 2013-12-01

Deskripsi

A high-speed counter-current chromatography (HSCCC) method was successfully developed for the preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus in one step. The purity of deoxyschizandrin was 98.5%, and the structure was identified by MS, UV and NMR. This method was simple, fast, convenient and appropriate to prepare pure compound as reference substances for related research on Schisandrae Sphenantherae Fructus. Keywords: Schisandrae Sphenantherae Fructus, High-speed counter-current chromatography (HSCCC), Deoxyschizandrin