The allosteric mechanism leading to an open-groove lipid conductive state of the TMEM16F scramblase

oleh: George Khelashvili, Ekaterina Kots, Xiaolu Cheng, Michael V. Levine, Harel Weinstein

Format: Article
Diterbitkan: Nature Portfolio 2022-09-01

Deskripsi

Molecular dynamics simulations reveal the allosteric mechanism leading to an open, lipid scrambling competent state of a mammalian TMEM16F.