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The title compound, C14H13N3O3, was synthesized by the condensation reaction of 2-hydroxy-4-methoxybenzaldehyde with isonicotinohydrazide in a methanol solution. The molecule of the compound displays a trans configuration with respect to the C=N and C—N bonds. The dihedral angle between the benzene and the pyridine rings is 27.3 (2)°. In the crystal, molecules are linked by N—H...N interactions into zigzag chains with graph-set notation C(7) along [010]. An intramolecular O—H...N hydrogen bond is observed.