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Interpretable and context-free deconvolution of multi-scale whole transcriptomic data with UniCell deconvolve
oleh: Daniel Charytonowicz, Rachel Brody, Robert Sebra
Format: | Article |
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Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
There is interest in measuring the influence of spatial cellular organization on pathophysiology, which is being accomplished through spatial transcriptomics. There the authors present UniCell Deconvolve, a pre-trained deep learning model that predicts cell identity and deconvolves cell type fractions using a 28 M cell database.