Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion

oleh: Anna Gorelick-Ashkenazi, Ron Weiss, Lena Sapozhnikov, Anat Florentin, Lama Tarayrah-Ibraheim, Dima Dweik, Keren Yacobi-Sharon, Eli Arama

Format: Article
Diterbitkan: Nature Portfolio 2018-07-01

Deskripsi

In addition to regulating programmed cell death, caspases also have non-apoptotic roles. Here, the authors show that low level caspase activity prevents cell migration to maintain tissue integrity.