Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P

oleh: Yangyang Li, Shichen Su, Yanqing Gao, Guoliang Lu, Hehua Liu, Xi Chen, Zhiwei Shao, Yixi Zhang, Qiyuan Shao, Xin Zhao, Jie Yang, Chulei Cao, Jinzhong Lin, Jinbiao Ma, Jianhua Gan

Format: Article
Diterbitkan: Nature Portfolio 2022-04-01

Deskripsi

HARP are member of protein-only RNase P, which catalyzes pre-tRNA 5’-end processing and maturation. Here, the authors present crystal structure and provide mechanistic insights into pre-tRNA binding and cleavage by HARP proteins.