Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>
oleh: Christa Litschko, Insa Budde, Monika Berger, Andrea Bethe, Julia Schulze, E. Alberto Alcala Orozco, Reza Mahour, Peter Goettig, Jana Indra Führing, Thomas Rexer, Rita Gerardy-Schahn, Mario Schubert, Timm Fiebig
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-06-01 |
Deskripsi
Economic synthesis platforms for the production of animal vaccines could help reduce the overuse and misuse of antibiotics in animal husbandry, which contributes greatly to the increase of antibiotic resistance. Here, we describe a highly versatile, easy-to-use mix-and-match toolbox for the generation of glycerol-phosphate-containing capsule polymers that can serve as antigens in glycoconjugate vaccines against Actinobacillus pleuropneumoniaeBibersteinia trehalosi