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<b>Aim:</b> To assess the results of corneal collagen cross-linking with riboflavin using ultraviolet - A light for keratoconus at one year in Indian eyes. <b> Materials and Methods:</b> Sixty-eight eyes of 41 patients with progressive keratoconus were included in this retrospective study. All eyes completed was 12 months of follow-up and 37 eyes had a one-year follow-up. The maximum follow-up was 16 months. Ocular examinations including refraction, best corrected visual acuity (BCVA), corneal topography, were recorded at each visit. <b> Results:</b> The mean age was 16.9 &#x00B1; 3.5 years (range 12-39 years) and the mean follow-up was 10.05 &#x00B1; 3.55 months (range six to 16 months). Thirty seven eyes with a follow-up of at least 12 months were analyzed. The preoperative values on the day of treatment were compared with postoperative values of the 12-month examination. This showed that BCVA improved at least one line in 54&#x0025; (20/37) of eyes and remained stable in 28&#x0025; (10/37) of eyes (<i> P</i> =0.006). Astigmatism decreased by a mean of 1.20 diopter (D) in 47&#x0025; (17/37) of eyes (<i> P</i> =0.005) and remained stable (within &#x00B1; 0.50 D) in 42&#x0025; (15/37) of eyes. The K value of the apex decreased by a mean of 2.73 D in 66&#x0025; (24/37) of eyes (<i> P</i> =0.004) and remained stable (within &#x00B1; 0.50 D) in 22&#x0025; (8/37) of eyes. The maximum K value decreased by a mean of 2.47 D in 54&#x0025; (20/37) of eyes (<i> P</i> =0.004) and remained stable (within &#x00B1; 0.50 D) in 38&#x0025; (14/37) of eyes. Corneal Wavefront analysis revealed that spherical and higher-order aberrations did not show significant variations in the follow-up period. The coma component showed a very significant reduction at six months after treatment and persisted throughout the follow-up period (<i> P</i> =0.003) <b> Conclusion:</b> The results show a stabilization and improvement in keratoconus after collagen cross-linking in Indian eyes. This suggests that it is an effective treatment for progressive keratoconus.