Design of stable and self-regulated microbial consortia for chemical synthesis

oleh: Xianglai Li, Zhao Zhou, Wenna Li, Yajun Yan, Xiaolin Shen, Jia Wang, Xinxiao Sun, Qipeng Yuan

Format: Article
Diterbitkan: Nature Portfolio 2022-03-01

Deskripsi

Stability and tunability are two desirable properties of microbial consortia-based bioproduction. Here, the authors integrate a caffeate-responsive biosensor into two and three strains coculture system to achieve autonomous regulation of strain ratios for coniferol and silybin/isosiltbin production, respectively.