Cryo-EM structures of KdpFABC suggest a K+ transport mechanism via two inter-subunit half-channels
oleh: C. Stock, L. Hielkema, I. Tascón, D. Wunnicke, G. T. Oostergetel, M. Azkargorta, C. Paulino, I. Hänelt
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-11-01 |
Deskripsi
The P-type ATPase subunit KdpB of KdpFABC hydrolyzes ATP while K+ transport was assumed to occur through channel-like subunit KdpA. Here, the authors show two cryo-EM structures of KdpFABC which suggest a translocation pathway through two inter-subunit half-channels formed by KdpA and KdpB.