The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins

oleh: Alexander Martin Geller, Inbal Pollin, David Zlotkin, Aleks Danov, Nimrod Nachmias, William B. Andreopoulos, Keren Shemesh, Asaf Levy

Format: Article
Diterbitkan: Nature Portfolio 2021-06-01

Deskripsi

The extracellular Contractile Injection System (eCIS) is a toxin-delivery particle that mediates interactions between bacteria and their invertebrate hosts. Here, the authors catalogue eCIS loci from 1,249 prokaryotic genomes, showing enrichment in non-pathogenic environmental microbes, and identifying eCIS-associated toxins that inhibit the growth of bacteria and/or yeast.