Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals

oleh: Ke Xu, Boyang Li, Kathleen A. McGinnis, Rachel Vickers-Smith, Cecilia Dao, Ning Sun, Rachel L. Kember, Hang Zhou, William C. Becker, Joel Gelernter, Henry R. Kranzler, Hongyu Zhao, Amy C. Justice, VA Million Veteran Program

Format: Article
Diterbitkan: Nature Portfolio 2020-10-01

Deskripsi

Genome-wide association studies (GWASs) for cigarette smoking have identified several hundred loci that account for a small proportion of the overall genetic risk. Here, the authors report a large GWAS for smoking trajectories and meta-analysis for smoking status, finding multiple plausible loci.