Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy
gan: Ramachandra M. Bhaskara, Paolo Grumati, Javier Garcia-Pardo, Sissy Kalayil, Adriana Covarrubias-Pinto, Wenbo Chen, Mikhail Kudryashev, Ivan Dikic, Gerhard Hummer
| Fformat: | Article |
|---|---|
| Cyhoeddwyd: | Nature Portfolio 2019-05-01 |
Disgrifiad
FAM134B/RETREG1 is a selective ER-phagy receptor that regulates the size and shape of the endoplasmic reticulum. Here authors use molecular modeling and molecular dynamics simulations to assemble a structural model for the reticulon-homology domain of FAM134B.