Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae
oleh: Sudeshna Saha, Alison Coady, Aniruddha Sasmal, Kunio Kawanishi, Biswa Choudhury, Hai Yu, Ricardo U. Sorensen, Jaime Inostroza, Ian C. Schoenhofen, Xi Chen, Anja Münster-Kühnel, Chihiro Sato, Ken Kitajima, Sanjay Ram, Victor Nizet, Ajit Varki
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-02-01 |
Deskripsi
All cells in vertebrates are coated with a dense array of glycans often capped with sugars called sialic acids. Sialic acids have many functions, including serving as a signal for recognition of “self” cells by the immune system, thereby guiding an appropriate immune response against foreign “nonself” and/or damaged cells.