Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins
oleh: Emma R. Hinkle, R. Eric Blue, Yi-Hsuan Tsai, Matthew Combs, Jacquelyn Davi, Alisha R. Coffey, Aladin M. Boriek, Joan M. Taylor, Joel S. Parker, Jimena Giudice
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-09-01 |
Deskripsi
Mechanical stretching of skeletal muscle cells induces extensive transcriptional and posttranscriptional changes in genes encoding proteins involved in transcription and muscle cell differentiation. SR proteins also exhibit altered transcription and phosphorylation in response to stretch.